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W1990 asked:


When an opiate is consumed, opiates tend to cause euphoria. But what actually causes this?

When opiates bind to opioid receptors in the brain, does the receptors trigger the release of Dopamine? Or is it just the opioid receptors, themselves causing euphoria?

I was curious about this.

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ok*sf asked:


Marinol is a physically non-toxic Schedule III (CIII) drug that can be prescribed for virtually anything a doctor feels that it might be appropriate for, yet most doctors seem reluctant to prescribe it until all other treatment options have failed (if at all).

These other treatment options are almost in all cases more physically toxic than is either Marinol or cannabis itself, so it can’t be because they’re afraid of bodily harm.

Opioid drugs, benzodiazepines, and many other drugs are severely physically addictive (whereas Marinol is not) and they’re prescribed routinely, so it can’t be because they’re afraid of addiction.

What gives with modern medicine? Why are we ignoring such a seemingly useful, yet benign substance?

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*Mommy to a Princess* asked:


I know this seems like an odd question, but I was reading about Carolyn Bessette-Kennedy, and her plane crash and was wandering how much pain she would have felt when they crashed? I feel so horrible for them, the fear that must have been going through them, I am hoping it was quick and painless but was wandering if anyone knows? How fast it might have happened? Pain?

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