What Is “Inflammatory Arthritis?”

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There is an old joke. It goes like this: “Neurologists diagnose the untreatable while rheumatologists treat the undiagnosable.” Nothing could be truer than when it comes to what is termed “inflammatory arthritis.”

Most rheumatologists tend to divide arthritis into two major categories: inflammatory and non-inflammatory. The latter category is also termed “degenerative” arthritis.

The major distinction is that inflammatory types of arthritis have a significant amount of inflammatory cells that attack the joints. These types of arthritis tend to cause more symptoms, particularly stiffness and pain. They also tend to be progressive. Oftentimes inflammatory types of arthritis are associated with constitutional symptoms, meaning low grade fever, weight loss, and fatigue. Inflammatory types of arthritis can also cause significant damage to internal organs. Disability and early death may be a consequence of some types of inflammatory arthritis. Examples of inflammatory arthritis are rheumatoid arthritis, systemic lupus erythematosus, psoriatic arthritis, gout, infectious arthritis, and ankylosing spondylitis.

Inflammatory types of arthritis can strike at any age.

Inflammatory types of arthritis have typical patterns although theoretically any joint in the body can be affected.

Inflammatory forms of arthritis may not be easy to categorize. Sometimes it will be obvious that inflammation is present and is a prominent component of the symptom complex. However, a specific diagnosis may not be apparent. Eventually most forms of inflammatory arthritis do “declare” themselves and ultimately fall into a category. But not always! This is a situation where a skilled diagnostician and clinician is worth their weight in gold!

On the other hand, non-inflammatory types of arthritis cause symptoms based on mechanical factors. Often degenerative arthritis affects weight-bearing joints such as the neck, low back, hips, and knees. It tends to occur in older people. While it may progress, it does so relatively slowly. It is rarely, if ever, associated with constitutional symptoms. In fact if constitutional symptoms are present, then either the patient has more than non-inflammatory arthritis or has another illness in addition to their arthritis. This is the type of arthritis people often associate with getting older.

Non-inflammatory types of arthritis may also be confusing some times. An example is a condition like fibromyalgia where the pain occurs pretty much all over. Symptomatic and subjective joint swelling may make the clinical diagnosis difficult.

The distinction between inflammatory and non-inflammatory arthritis is made on the basis of a careful history, physical examination, laboratory tests, and imaging procedures such as magnetic resonance imaging (MRI) and ultrasound.

Sometimes a patient can have both types of arthritis. For instance it is not uncommon for a patient with longstanding rheumatoid arthritis to also have degenerative arthritis (osteoarthritis) in a knee or hip.

Interestingly, when an arthroscope (small telescope) is used to visualize the interior of a joint, almost all types of arthritis have an inflammatory component to them. The extent and type of inflammatory change though varies from disease to disease.

The treatment for inflammatory arthritis will vary. While anti-inflammatory medicines are sometimes helpful, it may be necessary to start disease modifying drug therapy. Again the skill and experience of the arthritis specialist is paramount in determining which direction to head. Obviously, if the inflammatory arthritis becomes more well-defined, then treatment becomes easier to define as well.

The key point to remember is that if you do have arthritis, it’s important to seek the opinion of an expert arthritis specialist.



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categoriaPain Medicine commentoNo Comments dataAugust 9th, 2009
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Rheumatoid Arthritis Symptoms

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Over 100 known forms of arthritis are making millions of people suffer today. The most weakening of all forms is rheumatoid arthritis. Rheumatoid Arthritis Symptoms are joints that ache, throb, and eventually become deformed. Those who suffer from rheumatoid arthritis symptoms often find it hard to do everyday tasks, like taking a walk, or opening a car or jar. Some with rheumatoid arthritis have joints that are so deformed they are unable to even do the simplest job. No one knows what causes rheumatoid arthritis, but many believe it is the body’s immune system attacking the lining of your joints. This lining called the synovium.

Rheumatoid Arthritis Symptoms are more common in women than in men and will usually strike an adult between the ages of 20 to 50. That is the general criteria for rheumatoid arthritis symptom sufferers, but people over 50 and children can also be affected.

Rheumatoid arthritis symptoms usually develop in several joints at the same time. The first parts of your body that show signs of rheumatoid arthritis symptoms are usually your wrists, shoulders, hands, and feet. As the rheumatoid arthritis symptoms gradually get worse, it will attack the elbows, hips, neck, and jaw as well. It normally affects both sides at the same time.

Rheumatoid arthritis symptoms may appear as small lumps under skin where there are pressure points near your elbows, hands, feet, and Achilles tendons. Rheumatoid arthritis symptoms can develop in other areas of your body, but that’s where they start. At some point, you may experience rheumatoid nodules on the back of your scalp, around your knees, and even in your lungs. Rheumatoid arthritis symptoms can develop your salivary glands, linings of your lungs and heart, and sometimes the tear duct glands. These lumps are usually not painful. They can be the size of a pea or the size of a walnut.

Here are some symptoms of rheumatoid arthritis. Some of those Rheumatoid arthritis symptoms are:

Aching and stiffness of joints and muscles, especially after a time of rest. Pain and swelling in the joints, especially the smaller ones like in the hand. Loss of motion in the joints. Low-grade fever. Strength is lost in the muscles attached to the affected joints. Chronic fatigue when there is a flare-up of the disease. Deformity of joints. A general sense of just not feeling well. Unable to pinpoint exactly why they feel bad.

Any or all of these rheumatoid arthritis symptoms may come and go, but largely depend on what type of activity you are taking part in.

Rheumatoid arthritis symptoms do not go away, but it does come in “episodes.” A person suffering from rheumatoid arthritis symptoms may go into remission for a period, and then have another flare up of pain, swelling, weakness, and difficulty sleeping. You may experience a flare up, and then have several weeks or months of remission before it attacks again. There isn’t any reason why a person suffering from rheumatoid arthritis symptoms can’t be productive and useful lives while working around the attacks of your rheumatoid arthritis.

Some researchers theorize that rheumatoid arthritis could be the result of an infection or inflammation. When your body experiences an infection or inflammation, it sends white blood cells through the bloodstream and attacks the lining of the joints. Their usual job is to attack bacteria and viruses in the body instead it attacks the lining of the joints.

Other risk factors can increase your chances of having rheumatoid arthritis. Risk is increased as you age. The good news is if you are over the age of 80, the risk decreases.

You also have a higher risk of having rheumatoid arthritis if you are a woman, and if you have been exposed to a virus or bacteria. Although the disease is not inherited, there is evidence that specific genes you inherit could make you more prone to this arthritis.

Last, smoking cigarettes over a many years can also increase your chances of rheumatoid arthritis.

There isn’t a cure for rheumatoid arthritis yet. Scientists and researchers are still searching for the cause when that is found hopefully a cure would follow.

With the proper treatment, change in lifestyles, and a plan to prevent joints from deforming, a person experiencing rheumatoid arthritis symptoms may still be able to live a productive and long life. Deformity or swelling may limit your flexibility, but even in the most severe form of rheumatoid arthritis, you will probably still keep flexibility in most of your joints.



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categoriaHealth commentoNo Comments dataJuly 23rd, 2009
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Arthritis Treatment and Prevention

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Arthritis is a disease that causes pain and loss of movement of the joints. Arthritis is the leading cause of disability in people over the age of 55. Arthritis affects the movements you rely on for everyday activities. Arthritis refers to a group of more than 100 rheumatic diseases and other conditions that can cause pain, stiffness and swelling in the joints. There are many forms of arthritis, each of which has a different cause. Inflammatory arthritis is characterized by inflammation of tissues associated with joints. Connective tissue diseases, crystal deposition diseases, infectious arthritis, and spondyloarthropathies are examples of inflammatory arthritis. Rheumatoid arthritis and psoriatic arthritis are autoimmune diseases in which the body is attacking itself. Septic arthritis is caused by joint infection. Gouty arthritis is caused by deposition of uric acid crystals in the joint that results in subsequent inflammation. Rheumatoid arthritis (RA) is traditionally considered a chronic, inflammatory autoimmune disorder that causes the immune system to attack the joints. It is a disabling and painful inflammatory condition, which can lead to substantial loss of mobility due to pain and joint destruction. Arthritis sufferers include men and women, children and adults.

RA is a systemic disease, often affecting extra-articular tissues throughout the body including the skin, blood vessels, heart, lungs, and muscles. Psoriatic arthritis (or arthropathic psoriasis) is a type of inflammatory arthritis that affects around 20% of people suffering from the chronic skin condition psoriasis. It occurs more commonly in patients with tissue type HLA-B27. Treatment of psoriatic arthritis is similar to that of rheumatoid arthritis. More than 80% of patients with psoriatic arthritis will have psoriatic nail lesions characterised by pitting of the nails, or more extremely, loss of the nail itself (onycholysis). Psoriatic arthritis is said to be a seronegative spondyloarthropathy. Degenerative joint disease (osteoarthritis) is a ubiquitous joint disease characterized pathologically by deterioration of cartilage lining the joints and new bone formation beneath the cartilage. The disease is very common in older persons and is thought to be inherent in the aging process.Degenerative joint disease is marked by a progressive stiffness, loss of function, and destruction of the larger, weight-bearing joints of the body.

Nonarticular rheumatism is a group of diseases, also called soft-tissue rheumatisms, that includes tendonitis, bursitis, tenosynovitis, and fibrositis. Septic arthritis is the invasion of the joint space by an infectious agent. The usual etiology is bacterial, but viral, mycobacterial, and fungal arthritis occur occasionally. Bacteria are either carried by the bloodstream from an infectious focus elsewhere, introduced by a skin lesion. For bacterial infection, Pseudomonas aeruginosa has been found to infect joints, for example in children who have sustained a puncture wound. This bacteria also causes endocarditis. Septic arthritis should be suspected when one joint (monoarthritis) is affected and the patient is febrile. Gout is a painful condition that occurs when the body cannot eliminate a natural substance called uric acid. The excess uric acid forms needle-like crystals in the joints that cause swelling and severe pain. Gout most often affects the big toe, knee and wrist joints. Gout is a form of arthritis (an inflammation of the joints). Symptoms of arthritis include pain and limited function of joints. Inflammation of the joints from arthritis is characterized by joint stiffness, swelling, redness, and warmth. Tenderness of the inflamed joint can be present.

Arthritis Treatment and Prevention Tips

1.Treatment options is depending on the type of arthritis and include physical and occupational therapy, and medications (symptomatic or targeted at the disease process causing the arthritis).

2.Arthroplasty (joint replacement surgery) may be required in eroding forms of arthritis.

3.In conventional treatment, painkillers, such as paracetamol, are essential. Anti-inflammatory medications, such as ibuprofen, can help with episodes of more severe pain.

4.In recent years a new type of NSAID treatment, called Cox-2 inhibitors, has been launched. These were initially claimed to be less harmful to the stomach and many patients have found that they provided good pain relief for their arthritis.

5.Physiotherapy relieves pain and strengthens muscles around the damaged joint, helping the joint to work better.

6.Regular exercise is beneficial for the same reasons and, once pain is under control, easy to do.

7.Hip and knee replacements are common and usually involve a short hospital visit.

8.Disease-modifying drugs that slow disease progression are available for people with rheumatoid arthritis.



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